NETWORK CROWN ETHER POLYMERS WITH CENTRIC FUNCTIONAL GROUP (Ⅳ) SYNTHESIS OF NETWORK CROWN ETHER POLYMER WITH PENDANT DIETHYLAMINO THIAALKYL GROUP AND ITS PLATINUM COMPLEX*

The title polymer was prepared from 5-diethylamino-3-thia-pentyl glycidyl ether anddiethylene glycol bisglycidyl ether via ring-opening copolymerization. It was found that thisreaction could be catalyzed by sodium, but not Lewis acid. The obtained polymer can coordinatewith platinum compound, and the platinum complex is a new kind of catalyst for thehydrosilylation of olefins with triethoxysilane.     

Studies on the refolding of the reduced-denatured insulin with size exclusion chromatography

The refolding of the reduced-denatured insulin from bovine pancreas was investigated with the size exclusion chromatography (SEC). It was shown that the reduced-denatured insulin originally denatured with 7.0 mol·L-1 guanidine hydrochloride (GuHCI) or 8.0 mol·L-1 urea could not be refolded with a non-oxidized mobile phase. Although the oxidized and reduced glutathione (GSSG and GSH) were employed in the oxidized mobile phase, the reduced-denatured insulin still could not be renatured. However, in the presence of 2.0 mol·L-1 urea in the oxidized mobile phase employed, the reduced-denatured insulin can be refolded with SEC, and the aggregation of denatured insulin can be diminished by urea. In addition, the disul-fide exchange of reduced-denatured insulin also can be accelerated with GSSG/GSH in the oxidized mobile phase. The three disulfide bridges of insulin were formed correctly and the reduced-unfolded insulin can be renatured completely. The results were further tested with re-versed-phase liquid chromatography (RPLC) and hydrophobic interaction chromatography (HIC).     

Synthesis and Crystal Structure of an Ion-pair Compound:[H2(teta)]2+·[Ni(CN)4]2-·2H2O(teta=Meso-5,7,7,12,14,14-hexamethyl- 1,4,8,11-tetraazacyclotetradecane)

The ion-pair compound [H2(teta)]2+·[Ni(CN)4] 2-·2H2O (C20H42N8NiO2, teta = meso- 5,7,7,12,14,14-hexamethyl-1,4,8,11-tetraazacyclotetradecane) was synthesized and characterized by single-crystal X-ray diffraction. The crystal belongs to monoclinic, space group P21/n with a = 10.0784(10), b = 9.5411(7), c = 14.1010(14)(A), β= 106.752(2)o, V = 1298.4(2) (A)3, Mr = 485.33, Z = 2, Dc = 1.241 g/cm3,μ(MoKα) = 0.778 mm-1 and F(000) = 524. The structure was refined to R = 0.0391 and wR = 0.0870 for 2614 observed reflections with I > 2σ(I). The title compound contains one [Ni(CN)4]2- anion, one protonated macrocyclic tetraamine cation [H2(teta)]2+ and two water molecules. There are multiform hydrogen bonds in the compound to link the different components and stabilize the crystal structure.     

钐(II)类卡宾CH3SmCH2I与乙烯环丙烷化反应及溶剂化效应的理论研究

用密度泛函B3LYP方法研究了过渡金属钐类卡宾与乙烯的环丙烷化反应的机理. 对钐类卡宾试剂CH₃SmCH₂I和CH₂CH₂反应的反应物、中间体、过渡态和产物构型的全部结构几何参数进行了优化, 并计算了THF溶液的溶剂化效应, 用内禀反应坐标(IRC)计算和频率分析方法, 对过渡态进行了验证. 结果表明: CH₃SmCH₂I与CH₂CH₂环丙烷化反应按亚甲基转移机理(通道A)和卡宾金属化机理(通道B)都可以进行, 与锂类卡宾的反应机理相同, 通道A比通道B反应的势垒降低了14.65 kJ/mol. 溶剂化效应使通道B比通道A的反应势垒大幅度提高, 更有利于反应沿通道A进行, 而不利于通道B.     

话说葡萄酒中的抗癌明星——白藜芦醇

白藜芦醇被喻为继紫杉醇之后的又一新的绿色抗癌药物,是备受关注的一种具有重要生理活性的天然物质。主要介绍了其结构、性质、存在、生理功能及生产方法等。     

Effect of ligand structure of stationary phase of high performance hydrophobic interaction chromatography on renaturation efficiency of GuHCl-denaturedα-chymotrypsin

The renaturation of the denaturedα-chymotrypsin (α-Chy) with 1.7 mol·L-1 gua-nidine hydrochloride (GuHCI) by three kinds of stationary phase of high performance hydropho-bic interaction chromatography (STHIC) with a comparable hydrophobicity but different ligand structures was investigated. The obtained result indicates that the ligand structures of the three STHIC contribute to the renaturation efficiency ofα-Chy in the order of the end ligands PEG-600< phenyl group < tetrahydrofurfuryl alcohol (THFA).     

回旋速调管放大器输出腔的特性研究

 利用变截面波导的耦合模理论，根据输出腔中电场幅值分布函数所满足的微分方程组，编写了具有自动优化功能的计算程序，分析研究了不同渐变角度、考虑腔体损耗前后和输出腔与外电路失配时，谐振频率、腔体品质因数和高频场幅值沿轴分布的变化情况，为进一步研究高频场与电子注的互作用和输出腔奠定了基础。     

不同碱基物质对燃煤烟气脱氯的影响

实验探究NaOH、Na₂CO₃、NaHCO₃这三种常见的碱基物质在模拟燃煤烟气中的实际表现，发现三种碱基物质均具有一定的脱氯性能，NaOH、Na₂CO₃、NaHCO₃的脱氯性能依次下降，以脱氯效率70%为目标，使用三种碱基物质Na/Cl比分别需要达到5.8、7.1、8.7。高浓度SO₂的存在对烟气脱氯有竞争作用，随着SO₂浓度的提高，脱氯效率线性下降，不同碱基物质下，SO₂浓度对脱氯效率的影响规律基本一致，SO₂浓度每增加100 mg/m³，脱氯效率下降约1.4%。由于三种碱基物质达到相同脱氯效率时的Na/Cl比不同，综合考虑成本和溶解性，NaOH最具工业应用价值。     

不同波长条件KDP晶体的非线性光学性质研究

采用Z扫描方法系统的研究了KDP晶体在不同激光波长条件下的非线性光学性质.当λ=355 nm,功率密度为57.92 GW/cm2和λ=532 nm,功率密度为105.94 GW/cm2时,KDP晶体均呈现强烈的反饱和吸收和自聚焦效应,其非线性吸收系数和非线性折射率分别为6.50×10 -2cm/GW,1.17×10 -2cm/GW和8.02×10 -7cm2/GW,6. 14×10 -7cm2/GW;而在1064 nm波长,功率密度为347.95 GW/cm2时KDP晶体并未表现出明显的非线性性质.结果表明,在短波长的激光作用下,KDP晶体更容易产生非线性效应,双光子吸收是KDP晶体非线性吸收的主要机制.     

中国聚变工程实验堆水冷包层钢构件流道成形控制研究

针对CFETR水冷包层流道钢构件热等静压制备时易变形压塌问题，利用单轴扩散焊设备开展了焊接工艺参数优化试验。在此基础上，重新设计了流道焊接界面位置和尺寸，用两步热等静压扩散焊法制备出了流道变形可控的平板型第一壁钢构件模块。优化试验表明，低活化钢试样的固相扩散焊温度需高于950℃，焊后经过760℃/60min回火热处理试样力学性能可以得到有效回复。